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Zofran (ondansetron)

What is Zofran (ondansetron)?

Zofran is a brand name for the drug ondansetron. It is a medication used to prevent nausea and vomiting caused by chemotherapy, radiation therapy, and surgery. Zofran works by blocking the action of a natural substance in the body called serotonin, which can cause nausea and vomiting. Zofran is available in different forms such as tablets, oral dissolving tablets, and injections. It is only available with a prescription and should only be taken under the guidance of a healthcare provider.

When is Zofran used?

Zofran (ondansetron) is used to prevent and treat nausea and vomiting caused by various medical conditions such as chemotherapy, radiation therapy, surgery, and gastrointestinal illnesses. Some common uses of Zofran include:

  1. Nausea and vomiting related to chemotherapy: Zofran is often used in cancer patients to prevent or treat chemotherapy-induced nausea and vomiting.
  2. Nausea and vomiting related to radiation therapy: Zofran may be used to prevent or treat nausea and vomiting caused by radiation therapy.
  3. Post-operative nausea and vomiting: Zofran may be used to prevent nausea and vomiting after surgery.
  4. Gastrointestinal illnesses: Zofran may be used to treat nausea and vomiting caused by conditions such as gastroenteritis or gastroesophageal reflux disease (GERD).

It is important to note that Zofran is only available with a prescription and should be taken under the guidance of a healthcare provider. The medication should be used only for the condition it is prescribed for and according to the dosing instructions provided.

How long does Zofran stay in your system?

The half-life of Zofran (ondansetron) in the human body is approximately 4 to 6 hours. This means that half of the drug will be eliminated from the body during this time. Based on this, it can be estimated that it takes approximately 24 to 36 hours for the drug to be completely eliminated from the body after the last dose. However, the exact time it takes for Zofran to be eliminated from the body can vary based on individual factors such as age, weight, metabolism, and kidney and liver function. It is important to follow the dosing instructions provided by a healthcare provider and to not take more than prescribed.

What are contraindications with Zofran?

There are some contraindications for using Zofran (ondansetron) that should be considered before taking the medication. Some of these contraindications include:

  1. Hypersensitivity: Zofran should not be taken by anyone who is allergic or hypersensitive to ondansetron or any of its components.
  2. Serotonin syndrome: Zofran should not be used in combination with other medications that increase serotonin levels as it can cause a serious condition known as serotonin syndrome.
  3. Congenital long QT syndrome: Zofran should not be taken by individuals with a history of congenital long QT syndrome or those taking medications that can prolong the QT interval.
  4. Severe hepatic impairment: Zofran is metabolized by the liver, so it should be used with caution in individuals with severe liver impairment.
  5. Pregnancy: While Zofran is sometimes used to treat nausea and vomiting during pregnancy, it is not recommended for use in the first trimester due to possible associations with congenital abnormalities.

It is important to talk to a healthcare provider before taking Zofran to discuss any potential risks or concerns.

What are side effects of Zofran?

Like any medication, Zofran (ondansetron) can cause side effects in some people. Some of the most common side effects of Zofran include:

  1. Headache
  2. Fatigue
  3. Constipation
  4. Diarrhea
  5. Dizziness
  6. Rash or itching
  7. Dry mouth

Less common but more serious side effects of Zofran may include:

  1. Abnormal heart rhythm, including a prolonged QT interval
  2. Severe allergic reactions, including anaphylaxis
  3. Extrapyramidal reactions, such as muscle spasms, tremors, or rigidity
  4. Serotonin syndrome, a serious condition caused by an excess of serotonin in the body, which can cause fever, confusion, and seizures.

It is important to contact a healthcare provider if any side effects occur or if there are any concerns about taking Zofran. In some cases, a healthcare provider may need to adjust the dosage or switch to a different medication to manage side effects.

Therapy Menu

Our specialty mixtures

Our bags are not premixed allowing you to customize your therapies

Hydration

Target: Dehydration, mild nausea

Intravenous (IV)

  • IV Fluid – 1L 0.9% NaCl IV, 1L Lactated Ringers IV, or 1L Intralipid
  • Customize your therapy from solution base

Awake

Target: Dehydration, fatigue, jet lag, sports recovery

Intravenous (IV)

  • IV Fluid – 1L 0.9% NaCl IV
  • Vitamin B complex – 1mL IV in bag

Intramuscular (IM)

  • Vitamin B12 – 1,000mcg (1mg) IM

Slow IV Push

  • Taurine – 50mg IV push

Hangover

Target: Dehydration, nausea, migraine, vomiting, fatigue

Intravenous (IV)

  • IV Fluid – 1L Lactated Ringer (preferred)
  • Vitamin B complex – 1mL IV in bag
  • Magnesium – 200 mg in bag

Slow IV Push

  • Glutathione – 200mg IV push
  • Zofran – 4mg IV push
  • Toradol – 15-30mg IV push

Cold & Flu

Target: Dehydration, aches, pains, cough, congestion, fatigue, flu like symptoms

Intravenous (IV)

  • IV Fluid – 1L Lactated Ringer (preferred)
  • Vitamin B complex – 1mL IV in bag
  • Zinc – 2.5 mg IV in bag

Intramuscular (IM)

  • Vitamin B12 – 1,000mcg (1mg) IM

Slow IV Push

  • Glutathione – 200mg IV push
  • +/- Toradol – 15-30mg IV push

Immunity

Target: Dehydration, immunity, fatigue

Intravenous (IV)

  • IV Fluid – 1,000mL 0.9% NaCl (preferred)
  • Vitamin B complex – 1mL IV in bag
  • Vitamin C – 1,000 mg IV in bag
  • Zinc – 2.5 mg IV in bag

Intramuscular (IM)

  • Vitamin B12 – 1,000mcg (1mg) IM

Slow IV Push

  • Glutathione – 200mg IV push

Lipo-Mino Complex

Target: Dehydration, weight loss, energy, appetite regulation

Intravenous (IV)

  • IV Fluid – 1L 0.9% NaCl IV
  • Vitamin B complex – 1mL IV in bag

Intramuscular (IM)

  • LIPO-Mino – 1mL

Slow IV Push

  • Glutathione – 200mg IV push
  • Taurine – 50mg IV push

Food Poisoning & Stomach Flu

Target: Dehydration, nausea, vomiting, stomach pain

Intravenous (IV)

  • IV Fluid – 1L 0.9% NaCl IV
  • Vitamin B complex – 1mL IV in bag
  • Zinc – 2.5 mg IV in bag

Intramuscular (IM)

  • Vitamin B12 – 1,000mcg (1mg) IM

Slow IV Push

  • Glutathione – 200mg IV push
  • Zofran – 4mg IV push

Pepcid – 20mg IV push (dilute in 10mL)

Migraine

Target: Dehydration, migraine or headache

Intravenous (IV)

  • IV Fluid – 1L 0.9% Lactated Ringer (preferred)
  • Vitamin B complex – 1mL IV in bag
  • Magnesium – 200 mg IV in bag
  • Zinc – 2.5 mg IV in bag

Intramuscular (IM)

  • Vitamin B12 – 1,000mcg (1mg)

Slow IV Push

  • Zofran – 4mg IV push
  • Toradol – 15-30mg IV push
  • Benadryl– 50mg IV push

SHE

Target: Dehydration, menstrual cramps (dysmenorrhea)

Intravenous (IV)

  • IV Fluid – 1L 0.9% Lactated Ringer (preferred)
  • Vitamin B complex – 1mL IV in bag
  • Magnesium – 200 mg IV in bag
  • Zinc – 2.5 mg IV in bag

Intramuscular (IM)

  • Vitamin B12 – 1,000mcg (1mg)

Slow IV Push

  • Zofran – 4mg IV push
  • Toradol – 15-30mg IV push
  • Benadryl– 50mg IV push

Myers Cocktail

Target: Dehydration, wellness, fatigue, immunity

Intravenous (IV)

  • IV Fluid – 1L 0.9% NaCl (preferred)
  • Vitamin B complex – 1mL IV in bag
  • Vitamin C – 1,000mg IV in bag
  • Magnesium – 200mg IV in bag

Intramuscular (IM)

Vitamin B12 – 1,000mcg (1mg) IM

Superstar

Target: Dehydration, fatigue, immunity, acute symptoms, nausea, recovery, detox, and more

Intravenous (IV)

  • IV Fluid – 1L 0.9% NaCl IV
  • Vitamin B complex – 1mL IV in bag
  • Magnesium – 200mg IV in bag
  • Vitamin C – 2,000mg IV in bag
  • Zinc – 2.5mg IV in bag

Intramuscular (IM)

  • Vitamin B12 – 1,000mcg (1mg) IM

Slow IV Push:

  • Glutathione – 400mg IV push
  • Taurine – 50 mg IV push
  • If appropriate per symptom assessment or requested (INCLUDED in package charge):
  • Medicines
  • May substitute Lipo-Mino for B12 and B complex

Ultimate Superstar

Target: Dehydration, fatigue, immunity, acute symptoms, nausea, recovery, detox, and more at a max dose

Intravenous (IV)

  • IV Fluid – 1L 0.9% NaCl IV
  • Vitamin B complex – 1 mL IV in bag
  • Magnesium – 400mg IV in bag
  • Vitamin C – 10,000mg IV in bag
  • Zinc – 2.5mg IV in bag

Intramuscular (IM)

  • Vitamin B12 – 1,000mcg (1mg) IM

Slow IV Push:

  • Glutathione – 1,000mg IV push
  • Taurine – 100mg IV push
  • If appropriate per symptom assessment or requested (INCLUDED in package charge):
  • Medicines
  • May substitute Lipo-Mino for B12 and B complex

NAD+

Target: Dehydration, fatigue, immunity, acute symptoms, nausea, recovery, detox, and more

Intravenous (IV)

  • IV Fluid – 500mL 0.9% NaCl IV
  • NAD+: 500mg IV in bag
  • Additional NAD+: IV in bag ($1.50/mg additional
    charge)

NAD+ Superstar

Target: Dehydration, fatigue, immunity, acute symptoms, nausea, recovery, detox, anti-aging, accelerated cellular regeneration, and more

Intravenous (IV)

  • IV Fluid – 1L 0.9% NaCl IV
  • Vitamin B complex – 1mL IV in bag
  • Magnesium – 200mg IV in bag
  • Vitamin C – 2,000mg IV in bag
  • Zinc – 2.5mg IV in bag

Intramuscular (IM)

  • Vitamin B12 – 1,000mcg (1mg) IM

Slow IV Push:

  • Glutathione – 400mg IV push
  • Taurine – 50 mg IV push
  • If appropriate per symptom assessment or requested (INCLUDED in package charge):
  • Medicines
  • May substitute Lipo-Mino for B12 and B complex

Option 1: Calendar Date Request

Select any service if unsure, we can always edit your request later, the nurse comes fully equipped for any scenario. Your request on calendar will be pending until a nurse confirms. We will keep you updated via SMS on this process. After confirmation your nurse will reach out for introduction, consultation, and to provide an ETA. Reserve all medical questions for your nurse when paired. Please include any important medical history in notes section. Please be prepared to sign consent for IV therapy. If you apply on calendar you do not have to submit a request form. We will not charge your billing method until completion of therapy. A Same Day Service Fee ($35) is applied with every IV & IM therapy that is requested for same day. An After Hours Fee ($100)  is applied to all requests after 5pm.

Option 2: Request An Appointment

After submission we will pair you with a nurse that’s available in your area. Your nurse will reach out for introduction and consultation. Reserve all medical questions for your nurse when paired. Please include any important medical history in notes section. Please be prepared to sign consent for IV therapy. If you apply on calendar you do not have to submit a request form. We will not charge your billing method until completion of therapy. A Same Day Service Fee ($35) is applied with every IV & IM therapy that is requested for same day.

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